Tulio De Oliveira
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Tulio de Oliveira is a Brazilian, Portuguese, and South African permanent resident professor of
bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
at the
University of KwaZulu-Natal The University of KwaZulu-Natal (UKZN) is a university with five campuses in the province of KwaZulu-Natal in South Africa. It was formed on 1 January 2004 after the merger between the University of Natal and the University of Durban-Westville. ...
and
Stellenbosch University Stellenbosch University ( af, Universiteit Stellenbosch) is a public research university situated in Stellenbosch, a town in the Western Cape province of South Africa. Stellenbosch is the oldest university in South Africa and the oldest extant ...
, South Africa, and associate professor of global health at the
University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...
. He has studied outbreaks of
chikungunya Chikungunya is an infection caused by the ''Chikungunya virus'' (CHIKV). Symptoms include fever and joint pains. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a ra ...
,
dengue Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic ...
,
hepatitis B Hepatitis B is an infectious disease caused by the ''Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. Fo ...
and C,
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
,
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ...
,
yellow fever Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In ...
and
Zika Zika fever, also known as Zika virus disease or simply Zika, is an infectious disease caused by the Zika virus. Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever. Symptoms may include fever, red ...
. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
he led the team that confirmed the discovery of the
Beta variant The Beta variant, (B.1.351), was a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants initially believed to be of particular importance, it was first detected in the Nelson Mandela Bay metropolitan are ...
of the
COVID-19 virus Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a p ...
in 2020 and the
Omicron variant Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South Africa on 24 November 2021. It was first detected in Botswana and has spread to become the ...
in 2021. He gained fellowships to
Oxford University Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
, Wellcome Trust Sanger Institute, and
Edinburgh University The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 ...
, and in 2015 was appointed professor. In 2017, he founded the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) and in 2021 he founded the Centre for Epidemic Response and Innovation (CERI), to sequence and trace epidemics.


Early life

De Oliveira was born in Brazil. He earned a bachelor of science degree from the
Federal University of Rio Grande do Sul The Federal University of Rio Grande do Sul ( pt, Universidade Federal do Rio Grande do Sul, UFRGS) is a Brazilian public federal research university based in Porto Alegre, Rio Grande do Sul. UFRGS is among the largest and highest-rated univers ...
in Brazil. He completed his MSc and PhD at the Nelson R Mandela School of Medicine, University of KwaZulu-Natal.


Career

During his career he has studied outbreaks of
chikungunya Chikungunya is an infection caused by the ''Chikungunya virus'' (CHIKV). Symptoms include fever and joint pains. These typically occur two to twelve days after exposure. Other symptoms may include headache, muscle pain, joint swelling, and a ra ...
,
dengue Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Symptoms typically begin three to fourteen days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic ...
,
hepatitis B Hepatitis B is an infectious disease caused by the ''Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. Fo ...
and C,
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
,
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ...
,
yellow fever Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In ...
and
Zika Zika fever, also known as Zika virus disease or simply Zika, is an infectious disease caused by the Zika virus. Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever. Symptoms may include fever, red ...
. From 2004 to 2006 he was a Marie Curie research fellow at
Oxford University Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
. In 2015 he was a Newton advanced fellow at the Wellcome Trust Sanger Institute at
Edinburgh University The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 ...
and in the same year was appointed professor of
bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
at
University of KwaZulu-Natal The University of KwaZulu-Natal (UKZN) is a university with five campuses in the province of KwaZulu-Natal in South Africa. It was formed on 1 January 2004 after the merger between the University of Natal and the University of Durban-Westville. ...
. There, in 2017, he founded KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), which has sequenced and traced dengue, Zika, HIV and
tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...
, in addition to SARS-CoV-2. In 2018, the year prior to completing his fellowship at Edinburgh, he was appointed as an associate professor of Global Health at the
University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...
. In July 2021, he became a professor of bioinformatics at Stellenbosch University's School for Data Science and Computational Thinking. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
he led the team that confirmed the discovery of the
Beta variant The Beta variant, (B.1.351), was a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants initially believed to be of particular importance, it was first detected in the Nelson Mandela Bay metropolitan are ...
of the
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December ...
virus in late 2020. He has hypothesised that large groups of previously-infected people with declining immunity directly drive the emergence of variants of concern. If simultaneously there is a high level of transmission, then declining individual immunity may fail to prevent re-infection and if the virus is not cleared in enough people, new dangerous mutations may become more likely, as the virus survives and goes on to infect more people. Subsequently, as principal investigator and leader of the Network for Genomic Surveillance in South Africa, he led the team that confirmed and alerted authorities of the
Omicron variant Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South Africa on 24 November 2021. It was first detected in Botswana and has spread to become the ...
, first sequenced in Johannesburg's Lancet Laboratory, as a new variant in 2021. After first alerting authorities to the Omicron variant in South Africa, de Oliveira contended that the origin is unknown; he has "insisted that just because it was first detected in South Africa doesn't mean that's where it originated". He reported that it was possible that Omicron came from elsewhere as O. R. Tambo International Airport, Johannesburg, was the largest in Africa.


Recognition and awards

De Oliveira was included in a list of ten scientists with important roles in scientific developments in 2021 compiled by the scientific journal ''Nature. De Oliveira was included in a list of the leader of genomics surveillance as one of the ten breakthrough technologies in 2022 compiled by the scientific journal ''MIT_Technology_Review. He received the Gold Medal Award from the
South African Medical Research Council The South African Medical Research Council (SAMRC) is a para-statal medical research organisation in South Africa. The current president is professor Glenda Gray. The South African Medical Research Council was established in 1969 to act as an indep ...
(SAMRC) in 2022. In the same year, for his contributions to society, he received the Batho Pele Award from the Government of South Africa.


Further reading

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External links

* * * * Living people Year of birth missing (living people) Bioinformaticians University of Natal alumni Federal University of Rio Grande do Sul alumni Brazilian scientists Brazilian emigrants to South Africa University of KwaZulu-Natal alumni Academic staff of the University of KwaZulu-Natal Academic staff of Stellenbosch University University of Washington faculty


References

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